{"id":16044,"date":"2025-01-22T06:00:46","date_gmt":"2025-01-22T06:00:46","guid":{"rendered":"http:\/\/TheNextWeb=1411917"},"modified":"2025-01-22T06:00:46","modified_gmt":"2025-01-22T06:00:46","slug":"genomics-pioneer-steps-closer-to-dementia-treatment-breakthrough","status":"publish","type":"post","link":"https:\/\/www.londonchiropracter.com\/?p=16044","title":{"rendered":"Genomics pioneer steps closer to dementia treatment breakthrough"},"content":{"rendered":"\n<p><span>An Icelandic scaleup has sparked hopes of a breakthrough in dementia treatment after raising \u20ac26.5mn for groundbreaking research.<\/span><\/p>\n<p><span>Arctic Therapeutics (ATx) attracted the investment after pioneering a new approach to <a href=\"https:\/\/thenextweb.com\/news\/drug-discovery-might-be-the-best-use-of-ai-to-tackle-the-pandemic\" target=\"_blank\" rel=\"noopener\">drug development<\/a>. Founded in 2015, the company first analyses genomic data with bioinformatics \u2014 a blend of computer science and biology.<\/span><\/p>\n<p><span>After identifying disease-associated genes and proteins, ATx targets the root causes of a given condition.<\/span><\/p>\n<p><span>According to the scaleup, the process cuts the risks, costs, and time involved in developing treatments.<\/span><\/p>\n<div class=\"inarticle-wrapper channel-cta\">\n<div class=\"ica-text\" readability=\"0\"><a href=\"https:\/\/thenextweb.com\/conference\/tickets?utm_source=thenextweb-com&amp;utm_medium=display&amp;utm_campaign=global_tnw_media_event-registration_retargeting_early-bird_2025-tnw-conference-amsterdam&amp;utm_term=in-article\" data-event-category=\"Article\" data-event-action=\"In Article Block\" data-event-label=\"The next big thing? It might be you\u2026\" target=\"_blank\" readability=\"5\" rel=\"noopener\"><\/p>\n<p class=\"ica-text__title\">The next big thing? It might be you\u2026<\/p>\n<p>TNW Conference is here to support startups &amp; scaleups to become the next big thing. Be part of the journey. Price increase on Friday.<\/p>\n<p><\/a><\/div>\n<\/div>\n<p><span>The new financing could push the benefits closer towards patients. ATx said the Series A funds will advance two frontrunner drugs: AT-001 and AT-004.<\/span><\/p>\n<p><span>AT-001 has proven particularly promising. The treatment focuses on dementia caused by harmful accumulations of protein. Its primary target is amyloid-induced angiopathy, a condition characterised by proteins amassing in the walls of the brain\u2019s arteries.<\/span><\/p>\n<p><span>Taken orally, AT-001 disrupts and dissolves these harmful protein clusters. Consequently, the treatment could reduce the risks of dementia.<\/span><\/p>\n<p><span>ATx is confident of stalling the condition\u2019s progression. The company also believes the drug could delay dementia\u2019s onset \u2014 and even reverse its course.<\/span><\/p>\n<p><span>\u00cdvar H\u00e1konarson, the CEO and co-founder of ATx, said the treatment has \u201ctransformative potential.\u201d<\/span><\/p>\n<p><span>\u201cAT-001 offers hope for earlier intervention and even preventive use in individuals at high risk of developing dementia based on our biomarker signals,\u201d he told TNW.<\/span><\/p>\n<figure class=\"post-image post-mediaBleed aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-1411918 js-lazy\" src=\"https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2025\/01\/AT-Ivar-Hakonarso.jpg\" alt=\"Arctic Therapies co-founder and CEO \u00cdvar H\u00e1konarson\" width=\"1640\" height=\"1093\"><figcaption>Credit: ATx<\/figcaption><figcaption>H\u00e1konarson co-founded ATx&nbsp;in 2015 as a spin-off from the US-based Center for Applied Genomics (CAG). Credit: ATx<\/figcaption><noscript><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-1411918\" src=\"https:\/\/cdn0.tnwcdn.com\/wp-content\/blogs.dir\/1\/files\/2025\/01\/AT-Ivar-Hakonarso.jpg\" alt=\"Arctic Therapies co-founder and CEO \u00cdvar H\u00e1konarson\" width=\"1640\" height=\"1093\"><\/noscript><\/figure>\n<h2>Changing the trajectory of dementia<\/h2>\n<p><span>Tests on AT-001 are progressing rapidly. Last year, the European Medicines Agency (EMA) approved a new clinical trial that will probe the drug\u2019s effects on HCCAA \u2014 a rare form of familial dementia.<\/span><\/p>\n<p><span>ATx also plans to launch a clinical trial for AT-004. The study aims to show the treatment is effective and safe for acne, before expanding into other inflammatory skin diseases.<\/span><\/p>\n<p><span>ATx expects the new funds to accelerate the research.<\/span><\/p>\n<p><span>A syndicate of international <a href=\"https:\/\/thenextweb.com\/topic\/investor\" target=\"_blank\" rel=\"noopener\">investors<\/a> participated in the round. Among them is the European Commission\u2019s EIC Fund, which supports companies developing disruptive <a href=\"https:\/\/thenextweb.com\/topic\/tech\" target=\"_blank\" rel=\"noopener\">tech<\/a>.<\/span><\/p>\n<p><span>Svetoslava Georgieva, the chair of the EIC Fund Board, described the ATx financing as both an opportunity and a responsibility.<\/span><\/p>\n<p><span>\u201cIn Europe alone, dementia affects over 10 million people \u2014 placing immense strain on families, healthcare systems, and economies,\u201d she said in a statement.<\/span><\/p>\n<p><span>\u201cBy providing an equity investment in Arctic Therapeutics, the EIC Fund is supporting groundbreaking preventive treatments that have the potential to change the trajectory of this crisis, improve quality of life, and alleviate the burden on healthcare infrastructure worldwide.\u201d<\/span><\/p>\n<p> <a href=\"https:\/\/thenextweb.com\/news\/atx-raises-funds-for-dementia-alzheimers-treatment\">Source<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>An Icelandic scaleup has sparked hopes of a breakthrough in dementia treatment after raising \u20ac26.5mn for groundbreaking research. Arctic Therapeutics (ATx) attracted the investment after pioneering a new approach to drug development&#8230;.<\/p>\n","protected":false},"author":1,"featured_media":16045,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/www.londonchiropracter.com\/index.php?rest_route=\/wp\/v2\/posts\/16044"}],"collection":[{"href":"https:\/\/www.londonchiropracter.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.londonchiropracter.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.londonchiropracter.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.londonchiropracter.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=16044"}],"version-history":[{"count":0,"href":"https:\/\/www.londonchiropracter.com\/index.php?rest_route=\/wp\/v2\/posts\/16044\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.londonchiropracter.com\/index.php?rest_route=\/wp\/v2\/media\/16045"}],"wp:attachment":[{"href":"https:\/\/www.londonchiropracter.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=16044"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.londonchiropracter.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=16044"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.londonchiropracter.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=16044"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}